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SMI-4a

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842118

Background: A selective, ATP-competitive inhibitor Pim-1 (IC?? = 21 nM) and Pim-2 (IC?? = 100 nM) protein kinases. Blocks mTORC1 activity via activation of AMPK. SMI-4a has been found to inhibit prostate cancer cell growth and induce G1 phase cell-cycle… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
SMI-4a, Biochemical
Full Product Name
SMI-4a
Product Gene Name
Product Synonym Names
5E/Z)-[[3-(Trifluoromethyl)phenyl]methylene]-2,4-thiazolidinedione
Form/Format
Appearance: White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
273.23
CAS Number
327033-36-3
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD01152003
PubChem CID
1361334
Solubility/Reconstitution Instructions
DMSO (>10 mg/ml)
SMILES
C1=CC(=CC(=C1)C(F)(F)F)C=C2C(=O)NC(=O)S2
InChi
InChI=1S/C11H6F3NO2S/c12-11(13,14)7-3-1-2-6(4-7)5-8-9(16)15-10(17)18-8/h1-5H,(H,15,16,17)/b8-5-
InChi Key
NGJLOFCOEOHFKQ-YVMONPNESA-N
Handling
Protect from air and light

Structure of SMI-4a biochemical

SMI-4a Biochemical – Cat# MBS842118

Other Notes

Small volumes of SMI-4a biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SMI-4a purchase

MBS842118 is a biochemical targeting SMI-4a.
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