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HG-10-012-01

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842143

Background: Brain-permeable. HG-10-102-01 is a potent and selective inhibitor of wild-type LRRK2 and the G2019S mutant (IC?? values are ~20.3 nM and ~ 3.2 nM, respectively). It significantly inhibits Ser910 and Ser935 phosphorylation of both wild-type LRRK2… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
HG-10-012-01, Biochemical
Full Product Name
HG-10-012-01
Product Synonym Names
[4-[[5-Chloro-4-(methylamino)-2-pyrimidinyl]amino]-3-methoxyphenyl]-4-morpholinylmethanone
Form/Format
Appearance: White to off-white solid
Purity/Purification
>98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
377.83
CAS Number
1351758-81-0
Structure Available?
Y
Salt Form
No
Cell-Permeable?
Yes
Solubility/Reconstitution Instructions
DMSO (>30 mg/ml)
SMILES
O=C(N1CCOCC1)C(C=C2)=CC(OC)=C2NC3=NC=C(Cl)C(NC)=N3
InChi
InChI=1S/C17H20ClN5O3/c1-19-15-12(18)10-20-17(22-15)21-13-4-3-11(9-14(13)25-2)16(24)23-5-7-26-8-6-23/h3-4,9-10H,5-8H2,1-2H3,(H2,19,20,21,22)
InChi Key
YEVOZZZLKJKCCD-UHFFFAOYSA-N
Handling
Protect from air and light

Other Notes

Small volumes of HG-10-012-01 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HG-10-012-01 purchase

MBS842143 is a biochemical targeting HG-10-012-01.
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