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Epalrestat

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842164

Background: Epalrestat is an aldose reductase inhibitor (IC?? = 10 nM (rat lens) and 25 nM (human placenta). It reduces sorbitol accumulation in the sciatic nerve, erythrocytes and ocular tissue. May be used to prevent or slow the progression of diabetic… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Epalrestat, Biochemical
Full Product Name
Epalrestat
Product Synonym Names
2-[(5Z)-5-[(E)-3-phenyl-2-methylprop-2-enylidene]- 4-oxo-2-thioxo-3-thiazolidinyl]acetic acid
Form/Format
Appearance: Yellow solid
Purity/Purification
>=98% by TLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
319.4
CAS Number
82159-09-9
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
1549120
Solubility/Reconstitution Instructions
DMSO (~5 mg/ml)
SMILES
CC(=CC1=CC=CC=C1)C=C2C(=O)N(C(=S)S2)CC(=O)O
InChi
InChI=1S/C15H13NO3S2/c1-10(7-11-5-3-2-4-6-11)8-12-14(19)16(9-13(17)18)15(20)21-12/h2-8H,9H2,1H3,(H,17,18)/b10-7+,12-8-
InChi Key
CHNUOJQWGUIOLD-NFZZJPOKSA-N
Handling
Protect from light and air

Product Categories/Family for Epalrestat biochemical

Enzyme Inhibitors; Other Inhibitors; Other Inhibitors and Biochemicals; Enzyme Inhibitors; Other Inhibitors; Other Inhibitors and Biochemicals; Biochemicals (A-Z)

Structure of Epalrestat biochemical

Epalrestat Biochemical – Cat# MBS842164

Other Notes

Small volumes of Epalrestat biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Epalrestat purchase

MBS842164 is a biochemical targeting Epalrestat.
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