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RO4929097

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842194

Background: RO4929097 is a small molecule gamma-secretase inhibitor (IC?? = 4 nM). It binds to gamma-secretase and blocks the activation of Notch receptors, which may inhibit tumor cell proliferation. RO4929097 inhibits Notch processing in tumor cells as… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
RO4929097, Biochemical
Full Product Name
RO4929097
Product Gene Name
RO4929097 biochemical
Form/Format
Appearance: Off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
469.4
CAS Number
847925-91-1
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD18384976
PubChem CID
49867930
Solubility/Reconstitution Instructions
DMSO
SMILES
CC(C)(C(=O)NCC(C(F)(F)F)(F)F)C(=O)NC1C2=CC=CC=C2C3=CC=CC=C3NC1=O
InChi
InChI=1S/C22H20F5N3O3/c1-20(2,18(32)28-11-21(23,24)22(25,26)27)19(33)30-16-14-9-4-3-7-12(14)13-8-5-6-10-15(13)29-17(16)31/h3-10,16H,11H2,1-2H3,(H,28,32)(H,29,31)(H,30,33)/t16-/m0/s1
InChi Key
OJPLJFIFUQPSJR-INIZCTEOSA-N
Handling
Protect from air and light

Product Categories/Family for RO4929097 biochemical

Biochemicals; Enzyme Inhibitors; Secretase Inhibitors and biochemicals (A-Z)

Structure of RO4929097 biochemical

RO4929097 Biochemical – Cat# MBS842194

Other Notes

Small volumes of RO4929097 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RO4929097 purchase

MBS842194 is a biochemical targeting RO4929097.
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