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Ro 31-8220 methanesulfonate

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842204

Background: Cell-permeable. A potent bisindolylmaleimide inhibitor of protein kinase C (PKC) isoforms (IC?? = 5, 24, 14, 27, and 24 nM for PKC-alpha, PKC-betaI, PKC-betaII, PKC-gamma, and PKC-epsilon, respectively). It inhibits protein kinase A (PKA) (IC?? =… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Ro 31-8220 methanesulfonate, Biochemical
Full Product Name
Ro 31-8220 methanesulfonate
Product Synonym Names
2-{1-[3-(Amidinothio)propyl]-1H-indol-3-yl}-3-(1-methylindol-3-yl)maleimide methanesulfonate; Bisindolylmaleimide IX methanesulfonate; BIM IX
Form/Format
Appearance: Red solid
Purity/Purification
>=98% by NMR
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
553.65
CAS Number
138489-18-6
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD03788207
PubChem CID
11628205
Solubility/Reconstitution Instructions
DMSO (~ 100 mg/ml) or water (~ 5 mg/ml)
SMILES
CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)CCCSC(=N)N.CS(=O)(=O)O
InChi
InChI=1S/C25H23N5O2S.CH4O3S/c1-29-13-17(15-7-2-4-9-19(15)29)21-22(24(32)28-23(21)31)18-14-30(11-6-12-33-25(26)27)20-10-5-3-8-16(18)20;1-5(2,3)4/h2-5,7-10,13-14H,6,11-12H2,1H3,(H3,26,27)(H,28,31,32);1H3,(H,2,3,4)
InChi Key
SAWVGDJBSPLRRB-UHFFFAOYSA-N
Handling
Protect from light and air

Product Categories/Family for Ro 31-8220 methanesulfonate biochemical

Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Kinase C Inhibitors and Enzyme Inhibitors; Protein Kinase Inhibitors; GSK Inhibitors and Biochemicals; Biochemicals (A-Z)

Structure of Ro 31-8220 methanesulfonate biochemical

Ro 31-8220 Methanesulfonate Biochemical – Cat# MBS842204

Other Notes

Small volumes of Ro 31-8220 methanesulfonate biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ro 31-8220 methanesulfonate purchase

MBS842204 is a biochemical targeting Ro 31-8220 methanesulfonate.
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