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UNC0646

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842255

Background: UNC0646 is a potent and selective inhibitor of protein lysine methyltransferases G9a and GLP activities in vitro (IC??s = 6 and 15 nM, respectively) ; inhibits G9a/GLP-mediated dimethylation of histone 3 on lysine 9 in MDA-MB-231 cells (IC?? =… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
UNC0646, Biochemical
Full Product Name
UNC0646
Product Gene Name
UNC0646 biochemical
Product Synonym Names
N-(1-cyclohexyl-4-piperidinyl)-2-[hexahydro-4-(1-methylethyl)-1H-1,4-diazepin-1-yl]-6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinamine
Form/Format
Appearance: Pale yellow solid
Purity/Purification
>98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
621.9
CAS Number
1320288-17-2
Structure Available?
Y
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
53315882
Solubility/Reconstitution Instructions
DMSO (~50 mg/ml) or EtOH (~50 mg/ml)
SMILES
CC(C)N1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)C5CCCCC5)OC)OCCCN6CCCCC6
InChi
 InChI=1S/C36H59N7O2/c1-28(2)41-19-10-20-43(24-23-41)36-38-32-27-34(45-25-11-18-40-16-8-5-9-17-40)33(44-3)26-31(32)35(39-36)37-29-14-21-42(22-15-29)30-12-6-4-7-13-30/h26-30H,4-25H2,1-3H3,(H,37,38,39)
InChi Key
OUKWLRHRXOPODD-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for UNC0646 biochemical

Enzyme Inhibitors; Methyltransferase Inhibitors and Biochemicals; Enzyme Inhibitors; Methyltransferase Inhibitors and Epigenetics; Writer Enzymes; Protein Lysine Methyltransferases (PKMTs); PKMT Inhibitors and Biochemicals; Biochemicals (A-Z)

Structure of UNC0646 biochemical

UNC0646 Biochemical – Cat# MBS842255

Other Notes

Small volumes of UNC0646 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UNC0646 purchase

MBS842255 is a biochemical targeting UNC0646.
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