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RepSox

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842304

Background: Cell-permeable. A TGF-beta type I receptor (ALK5) inhibitor. Inhibits ALK5 autophosphorylation (IC?? = 4 nM). Can replace one of the four reprogramming factors Sox-2. RepSox has been successfully used in the direct reprogramming of mouse… More details

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Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
RepSox, Biochemical
Full Product Name
RepSox
Product Gene Name
RepSox biochemical
Product Synonym Names
2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine; E-616452
Form/Format
Appearance: Off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
287.32
CAS Number
446859-33-2
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD09037561
PubChem CID
449054
Solubility/Reconstitution Instructions
DMSO (>20 mg/ml)
SMILES
CC1=CC=CC(=N1)C2=C(C=NN2)C3=NC4=C(C=C3)N=CC=C4
InChi
InChI=1S/C17H13N5/c1-11-4-2-5-16(20-11)17-12(10-19-22-17)13-7-8-14-15(21-13)6-3-9-18-14/h2-10H,1H3,(H,19,22)
InChi Key
LBPKYPYHDKKRFS-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for RepSox biochemical

Stem Cell Research Tools; Stem Cell Fate Regulators; Induced Pluripotent Stem (iPS) cells and Reprogramming and Biochemicals (A-Z)

Structure of RepSox biochemical

RepSox Biochemical – Cat# MBS842304

Other Notes

Small volumes of RepSox biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RepSox purchase

MBS842304 is a biochemical targeting RepSox.
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