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EPZ015666

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602359

EPZ015666 (GSK3235025) is a potent, selective, orally available inhibitor of PRMT5 with Ki/IC50 of 5/22 nM. More details

$240 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
EPZ015666, Biochemical
Full Product Name
EPZ015666
Product Synonym Names
EPZ-015666; GSK3235025
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
383.4442
Suitability
DMSO
Target
HMTase
Receptor
PRMT5
Chemical Name
4-Pyrimidinecarboxamide, N-[(2S)-3-(3, 4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-6-(3-oxetanylamino)
SMILES
O=C(C1=NC=NC(NC2COC2)=C1)NC[C@H](O)CN3CC4=C(C=CC=C4)CC3
Molecular Formula
C20H25N5O3
CAS Number
1616391-65-1

Product Categories/Family for EPZ015666 biochemical

Chromatin/Epigenetic; Cancer

Structure of EPZ015666 biochemical

EPZ015666 Biochemical – Cat# MBS3602359

Product References and Citations for EPZ015666 biochemical

1. Chan-Penebre E, et al. Nat Chem Biol. 2015 Jun; 11 (6):432-7.
2. Kryukov GV, et al. Science. 2016 Mar 11; 351 (6278):1214-8.
3. Chan-Penebre E, et al. ACS Med Chem Lett. 2015 Dec 2; 7 (2):162-6.
4. Gulli  A, et al. Leukemia. 2018 Apr; 32 (4):996-1002.

Other Notes

Small volumes of EPZ015666 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EPZ015666 purchase

MBS3602359 is a biochemical targeting EPZ015666.
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