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TAK-632

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842386

Background: A selective pan-RAF inhibitor with IC?? Values: 2.4 nM (BRAF V600E); 1.4 nM (C-RAF); 160 nM (VEGFR). TAK-632 displays significant cellular activity against mutated BRAF or mutated NRAS cancer cell lines. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
TAK-632, Biochemical
Full Product Name
TAK-632
Product Gene Name
TAK-632 biochemical
Product Synonym Names
N-(7-cyano-6-(4-fluoro-3-(2-(3-(trifluoromethyl)phenyl)acetamido)phenoxy)benzo[d]thiazol-2-yl)cyclopropanecarboxamide
Form/Format
Appearance: White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
554.51
CAS Number
1228591-30-7
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
Solubility/Reconstitution Instructions
DMSO (>50 mg/ml)
SMILES
O=C(NC1=C(F)C=CC(OC2=CC=C(N=C(NC(C3CC3)=O)S4)C4=C2C#N)=C1)CC5=CC(C(F)(F)F)=CC=C5
InChi
InChI=1S/C27H18F4N4O3S/c28-19-7-6-17(12-21(19)33-23(36)11-14-2-1-3-16(10-14)27(29,30)31)38-22-InChI=1S/C27H18F4N4O3S/c28-19-7-6-17(12-21(19)33-23(36)11-14-2-1-3-16(10-14)27(29,30)31)38-22-9-8-20-24(18(22)13-32)39-26(34-20)35-25(37)15-4-5-15/h1-3,6-10,12,15H,4-5,11H2,(H,33,36)(H,34,35,37)
InChi Key
OJFKUJDRGJSAQB-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for TAK-632 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Raf Kinase Inhibitors and Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Raf Kinase Inhibitors and Biochemicals; Biochemicals (A-Z)

Structure of TAK-632 biochemical

TAK-632 Biochemical – Cat# MBS842386

Other Notes

Small volumes of TAK-632 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TAK-632 purchase

MBS842386 is a biochemical targeting TAK-632.
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