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PF-04691502

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842393

Background: A potent, ATP-competitive PI3K/mTOR dual inhibitor with broad antitumor activity. PF-04691502 potently inhibits recombinant class I PI3K and mTOR in biochemical assays and suppresses transformation of avian fibroblasts mediated by wild-type PI3K… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PF-04691502, Biochemical
Full Product Name
PF-04691502
Product Synonym Names
2-amino-8-((1r,4r)-4-(2-hydroxyethoxy)cyclohexyl)-6-(6-methoxypyridin-3-yl)-4-methylpyrido[2,3-d]pyrimidin-7(8H)-one
Form/Format
Appearance: Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
425.48
CAS Number
1013101-36-4
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
25033539
Solubility/Reconstitution Instructions
DMSO (>10 mg/ml)
SMILES
CC1=C2C=C(C(=O)N(C2=NC(=N1)N)C3CCC(CC3)OCCO)C4=CN=C(C=C4)OC
InChi
InChI=1S/C22H27N5O4/c1-13-17-11-18(14-3-8-19(30-2)24-12-14)21(29)27(20(17)26-22(23)25-13)15-4-6-16(7-5-15)31-10-9-28/h3,8,11-12,15-16,28H,4-7,9-10H2,1-2H3,(H2,23,25,26)
InChi Key
XDLYKKIQACFMJG-UHFFFAOYSA-N
Handling
Protect from light and moisture

Product Categories/Family for PF-04691502 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; PI3K/mTOR Inhibitors and Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; PI3K/mTOR Inhibitors and Biochemicals (A-Z)

Structure of PF-04691502 biochemical

Pf-04691502 Biochemical – Cat# MBS842393

Other Notes

Small volumes of PF-04691502 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PF-04691502 purchase

MBS842393 is a biochemical targeting PF-04691502.
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