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AG 1478

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842397

Background: Cell-permeable. A potent EGFR Tyrosine Kinase (TK) inhibitor with an IC?? of 3 nM. Only weakly inhibits PDGFR and HER2-NEU kinases (IC?? >100 uM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AG 1478, Biochemical
Full Product Name
AG 1478
Product Gene Name
AG 1478 biochemical
Product Synonym Names
4-(3'-Chloroanilino)-6,7-dimethoxyquinazoline; Tyrphostin AG 1478
Form/Format
Appearance: White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 48 months
Molecular Weight
315.75
CAS Number
175178-82-2
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD00270914
PubChem CID
53429216
Solubility/Reconstitution Instructions
DMSO (50 mg/ml)
SMILES
COC1=C(C=C2C(=C1)C(=NC=N2)CC3=CC(=CC=C3)Cl)OC
InChi
InChI=1S/C17H15ClN2O2/c1-21-16-8-13-14(7-11-4-3-5-12(18)6-11)19-10-20-15(13)9-17(16)22-2/h3-6,8-10H,7H2,1-2H3
InChi Key
DOBKKEHYAFERJH-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for AG 1478 biochemical

Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase Inhibitors and Biochemicals (A-Z)

Structure of AG 1478 biochemical

AG 1478 Biochemical – Cat# MBS842397

Other Notes

Small volumes of AG 1478 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AG 1478 purchase

MBS842397 is a biochemical targeting AG 1478.
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