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Gambogic acid

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842410

Background: Gambogic acid is a plant-derived natural product that acts as a caspase activator and apoptosis inducer, which causes an irreversible arrest in the G2/M phase of the cell cycle. It causes a decrease of Bcl-2 gene and an increase in Bax gene… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Gambogic acid, Biochemical
Full Product Name
Gambogic acid
Product Synonym Names
(Z)-4-((1S,3aR,5S,11R,14aS)-8-hydroxy-2,2,11-trimethyl-13-(3-methylbut-2-en-1-yl)-11-(4-methylpent-3-en-1-yl)-4,7-dioxo-2,3a,4,5,7,11-hexahydro-1H-1,5-methanofuro[3,2-g]pyrano[3,2-b]xanthen-3a-yl)-2-methylbut-2-enoic acid
Form/Format
Appearance: Orange solid
Purity/Purification
>=95%
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
628.75
CAS Number
2752-65-0
Structure Available?
Y
Salt Form
No
Cell-Permeable?
Y
PubChem CID
9852185
Solubility/Reconstitution Instructions
DMSO (>25 mg/ml) or EtOH (~20 mg/ml)
SMILES
CC(=CCCC1(C=CC2=C(O1)C(=C3C(=C2O)C(=O)C4=CC5CC6C4(O3)C(C5=O)(OC6(C)C)CC=C(C)C(=O)O)CC=C(C)C)C)C
InChi
InChI=1S/C38H44O8/c1-20(2)10-9-15-36(8)16-14-24-29(39)28-30(40)26-18-23-19-27-35(6,7)46-37(33(23)41,17-13-22(5)34(42)43)38(26,27)45-32(28)25(31(24)44-36)12-11-21(3)4/h10-11,13-14,16,18,23,27,39H,9,12,15,17,19H2,1-8H3,(H,42,43)/b22-13-/t23-,27+,36-,37+,38-/m1/s1
InChi Key
GEZHEQNLKAOMCA-RRZNCOCZSA-N
Handling
Protect from air and light

Other Notes

Small volumes of Gambogic acid biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Gambogic acid purchase

MBS842410 is a biochemical targeting Gambogic acid.
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