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Combretastatin A4

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842444

Background: A vascular disrupting, antineoplastic and microtubule-depolymerizing agent. Binds to tubulin dimers and prevents microtubule polymerization, resulting in mitotic arrest and apoptosis in endothelial cells. In addition, it disrupts the engagement of… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Combretastatin A4, Biochemical
Full Product Name
Combretastatin A4
Product Synonym Names
2-Methoxy-5-[(1Z)-2-(3,4,5-trimetho-xyphenyl)ethenyl]phenol; CRC 87-09; NSC 817373
Form/Format
Appearance: White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
316.35
CAS Number
117048-59-6
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD03453309
PubChem CID
5351344
Solubility/Reconstitution Instructions
DMSO (100 mM) or EtOH (100 mM)
SMILES
COC1=C(C=C(C=C1)C=CC2=CC(=C(C(=C2)OC)OC)OC)O
InChi
InChI=1S/C18H20O5/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11,19H,1-4H3/b6-5-
InChi Key
HVXBOLULGPECHP-WAYWQWQTSA-N
Handling
Protect from light and moisture

Product Categories/Family for Combretastatin A4 biochemical

Enzyme Inhibitors; Microtubule Inhibitors and Biochemicals; Enzyme Inhibitors; Microtubule Inhibitors and Biochemicals; Anticancer Agents and Biochemicals (A-Z)

Structure of Combretastatin A4 biochemical

Combretastatin A4 Biochemical – Cat# MBS842444

Other Notes

Small volumes of Combretastatin A4 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Combretastatin A4 purchase

MBS842444 is a biochemical targeting Combretastatin A4.
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