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TAK-733

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842445

Background: A potent, selective, non-ATP competitive, allosteric MEK inhibitor. TAK-733 selectively binds to and inhibits the activity of MEK1/2, preventing the activation of MEK1/2-dependent effector proteins and transcription factors, which may result in… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
TAK-733, Biochemical
Full Product Name
TAK-733
Product Gene Name
TAK-733 biochemical
Product Synonym Names
(R)-3-(2,3-dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione
Form/Format
Appearance: Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
504.23
CAS Number
1035555-63-5
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
24963252
Solubility/Reconstitution Instructions
DMSO (>100 mg/ml)
SMILES
CN1C2=C(C(=C(C1=O)F)NC3=C(C=C(C=C3)I)F)C(=O)N(C=N2)CC(CO)O
InChi
InChI=1S/C17H15F2IN4O4/c1-23-15-12(16(27)24(7-21-15)5-9(26)6-25)14(13(19)17(23)28)22-11-3-2-8(20)4-10(11)18/h2-4,7,9,22,25-26H,5-6H2,1H3/t9-/m1/s1
InChi Key
RCLQNICOARASSR-SECBINFHSA-N
Handling
Protect from air and light

Product Categories/Family for TAK-733 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; MAP Kinase/MEK Inhibitors and Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; MAP Kinase/MEK Inhibitors and Signaling Pathways; MAP Kinase Pathway; MAP Kinase/MEK Inhibitors and Biochemicals; Bioch

Structure of TAK-733 biochemical

TAK-733 Biochemical – Cat# MBS842445

Other Notes

Small volumes of TAK-733 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TAK-733 purchase

MBS842445 is a biochemical targeting TAK-733.
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