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Splitomicin

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842450

Background: Potent inhibitor of yeast NAD?-dependent histone deacetylase Sir2p (IC?? = 60 uM). Sensitizes mammalian cells to a variety of DNA-damaging agents by abrogating Sir2p activity on p53. Acts by either altering or blocking access to the acetylated… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Splitomicin, Biochemical
Full Product Name
Splitomicin
Product Synonym Names
1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one
Form/Format
Appearance: White to off-white solid
Purity/Purification
>=98%
Preparation and Storage
4 degree C
Shelf Life: 24 months
Molecular Weight
198.2
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD08705254
PubChem CID
5269
Solubility/Reconstitution Instructions
DMSO (100 mg/ml)
SMILES
C1CC(=O)OC2=C1C3=CC=CC=C3C=C2
InChi
InChI=1S/C13H10O2/c14-13-8-6-11-10-4-2-1-3-9(10)5-7-12(11)15-13/h1-5,7H,6,8H2
InChi Key
ISFPDBUKMJDAJH-UHFFFAOYSA-N
Handling
Protect from air and moisture

Other Notes

Small volumes of Splitomicin biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Splitomicin purchase

MBS842450 is a biochemical targeting Splitomicin.
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