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Lomitapide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842495

Background: Lomitapide is a small molecule that lowers total cholesterol levels by inhibiting microsomal triglyceride transfer protein (MTTP) and preventing the assembly of apoB-containing lipoproteins and VLDL synthesis. Lomitapide is also a substrate and… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Lomitapide, Biochemical
Full Product Name
Lomitapide
Product Synonym Names
N-(2,2,2-trifluoroethyl)-9-(4-(4-(4'-(trifluoromethyl)-[1,1'-biphenyl]-2-ylcarboxamido)piperidin-1-yl)butyl)-9H-fluorene-9-carboxamide; BMS201038; AEGR773
Form/Format
Appearance: Off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
693.72
CAS Number
182431-12-5
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
9853053
Solubility/Reconstitution Instructions
DMSO (~ 5 mg/ml)
SMILES
C1CN(CCC1NC(=O)C2=CC=CC=C2C3=CC=C(C=C3)C(F)(F)F)CCCCC4(C5=CC=CC=C5C6=CC=CC=C64)C(=O)NCC(F)(F)F
InChi
InChI=1S/C39H37F6N3O2/c40-38(41,42)25-46-36(50)37(33-13-5-3-10-30(33)31-11-4-6-14-34(31)37)21-7-8-22-48-23-19-28(20-24-48)47-35(49)32-12-2-1-9-29(32)26-15-17-27(18-16-26)39(43,44)45/h1-6,9-18,28H,7-8,19-25H2,(H,46,50)(H,47,49)
InChi Key
MBBCVAKAJPKAKM-UHFFFAOYSA-N
Handling
Protect from air and light

Other Notes

Small volumes of Lomitapide biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Lomitapide purchase

MBS842495 is a biochemical targeting Lomitapide.
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