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ICG-001

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842507

Background: A specific inhibitor of Wnt/beta-catenin signaling pathway. It down-regulates beta-catenin/T cell factor signaling by specifically binding to cyclic AMP response element-binding protein (CBP). ICG-001 selectively induces apoptosis in transformed… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
ICG-001, Biochemical
Full Product Name
ICG-001
Product Gene Name
ICG-001 biochemical
Product Synonym Names
(6S,9aS)-Hexahydro-6-[(4-hydroxyphe-nyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(-phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-c-arboxamide
Form/Format
Appearance: White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
548.63
CAS Number
847591-62-2
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
11238147
Solubility/Reconstitution Instructions
DMSO (~50 mg/ml) or EtOH (~25 mg/ml)
SMILES
C1CN(C2CN(C(=O)C(N2C1=O)CC3=CC=C(C=C3)O)CC4=CC=CC5=CC=CC=C54)C(=O)NCC6=CC=CC=C6
InChi
InChI=1S/C33H32N4O4/c38-27-15-13-23(14-16-27)19-29-32(40)35(21-26-11-6-10-25-9-4-5-12-28(25)26)22-30-36(18-17-31(39)37(29)30)33(41)34-20-24-7-2-1-3-8-24/h1-16,29-30,38H,17-22H2,(H,34,41)/t29-,30+/m0/s1
InChi Key
HQWTUOLCGKIECB-XZWHSSHBSA-N
Handling
Protect from air and moisture

Product Categories/Family for ICG-001 biochemical

Enzyme Inhibitors; Wnt Signaling Inhibitors and Biochemicals; Enzyme Inhibitors; Wnt Signaling Inhibitors and Diabetes; Obesity & Metabolic Syndrome; Signaling Pathways in Diabetes and Obesity; GSK-3/Wnt Signaling; Wnt/b-Catenin Signaling Pathway Modulato

Structure of ICG-001 biochemical

ICG-001 Biochemical – Cat# MBS842507

Other Notes

Small volumes of ICG-001 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ICG-001 purchase

MBS842507 is a biochemical targeting ICG-001.
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