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GSK-3 Inhibitor, AR-A014418

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842513

Background: Cell-permeable. A selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC?? = 104 nM). Inhibition is competitive with respect to ATP (Ki = 38nM). Exhibits specificity for GSK-3 over cdk2 and cdk5 (IC?? values are > 100 muM) and over 26 other… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GSK-3 Inhibitor, AR-A014418, Biochemical
Full Product Name
GSK-3 Inhibitor, AR-A014418
Product Synonym Names
N-[(4-Methoxyphenyl)methyl]-N'-(5-nitro-2-thiazolyl)urea
Form/Format
Appearance: Off-white solid
Purity/Purification
>=98% by TLC
Preparation and Storage
At -20 degree C
Shelf Life: 48 months
Molecular Weight
308.31
CAS Number
487021-52-3
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD08277040
PubChem CID
448014
Solubility/Reconstitution Instructions
DMSO (30 mg/ml)
SMILES
COC1=CC=C(C=C1)CNC(=O)NC2=NC=C(S2)[N+](=O)[O-]
InChi
InChI=1S/C12H12N4O4S/c1-20-9-4-2-8(3-5-9)6-13-11(17)15-12-14-7-10(21-12)16(18)19/h2-5,7H,6H2,1H3,(H2,13,14,15,17)
InChi Key
YAEMHJKFIIIULI-UHFFFAOYSA-N
Handling
Protect from light and air

Product Categories/Family for GSK-3 Inhibitor, AR-A014418 biochemical

Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; GSK Inhibitors and Diabetes; Obesity & Metabolic Syndrome; Signaling Pathways in Diabetes and Obesity; GSK-3/Wnt Signaling; GSK-3 Inhibitors Biochemicals; Biochemicals (A-Z)

Structure of GSK-3 Inhibitor, AR-A014418 biochemical

GSK-3 Inhibitor, AR-A014418 Biochemical – Cat# MBS842513

Other Notes

Small volumes of GSK-3 Inhibitor, AR-A014418 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSK-3 Inhibitor, AR-A014418 purchase

MBS842513 is a biochemical targeting GSK-3 Inhibitor, AR-A014418.
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