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GW788388

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842520

Background: GW788388 is a potent and selective inhibitor of transforming growth factor beta receptor I (TGF-betaR1) (activin receptor-like kinase 5, ALK5) (IC?? = 18 nM). Also inhibits TGF-beta type II receptor and activin type II receptor activities, but… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GW788388, Biochemical
Full Product Name
GW788388
Product Gene Name
GW788388 biochemical
Product Synonym Names
4-[4-[3-(2-Pyridinyl)-1H-pyrazol-4-yl]-2-pyridinyl]-N-(tetrahydro-2H-pyran-4-yl)-benzamide
Form/Format
Appearance: Off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
425.48
CAS Number
452342-67-5
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
yes
MDL Number
MFCD20527321
PubChem CID
10202642
Solubility/Reconstitution Instructions
DMSO (>40 mg/ml)
SMILES
C1COCCC1NC(=O)C2=CC=C(C=C2)C3=NC=CC(=C3)C4=C(NN=C4)C5=CC=CC=N5
InChi
InChI=1S/C25H23N5O2/c31-25(29-20-9-13-32-14-10-20)18-6-4-17(5-7-18)23-15-19(8-12-27-23)21-16-28-30-24(21)22-3-1-2-11-26-22/h1-8,11-12,15-16,20H,9-10,13-14H2,(H,28,30)(H,29,31)
InChi Key
SAGZIBJAQGBRQA-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for GW788388 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase InhibitorsEnzyme Inhibitors; Enzyme Inhibitors (A-Z) Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase InhibitorsBiochemicals; Enzyme Inhibitors; Enzym

Structure of GW788388 biochemical

GW788388 Biochemical – Cat# MBS842520

Other Notes

Small volumes of GW788388 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GW788388 purchase

MBS842520 is a biochemical targeting GW788388.
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