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Cyclosporine A

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842564

Background: A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A-cyclophilin complex that inhibits calcineurin (protein phosphatase 2B. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Cyclosporine A, Biochemical
Full Product Name
Cyclosporine A
Product Synonym Names
Antibiotic S 7481F1; Cyclosporine
Form/Format
Appearance: White solid
Purity/Purification
>99%
Preparation and Storage
4 degree C
Shelf Life: 12 months
Molecular Weight
1202.6
CAS Number
59865-13-3
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD00274558
PubChem CID
5284373
Solubility/Reconstitution Instructions
DMSO and EtOH
SMILES
CCC1C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)CC=CC)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
InChi
InChI=1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25+/t40-,41+,42-,43+,44+,45+,46+,47+,49+,50+,51+,52-/m1/s1
InChi Key
PMATZTZNYRCHOR-CGLBZJNRSA-N
Handling
Protect from light and air

Product Categories/Family for Cyclosporine A biochemical

Molecular Biology Tools; Molecular Biology Biochemicals; Antibiotics

Structure of Cyclosporine A biochemical

Cyclosporine A Biochemical – Cat# MBS842564

Other Notes

Small volumes of Cyclosporine A biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cyclosporine A purchase

MBS842564 is a biochemical targeting Cyclosporine A.
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