• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Bromodomain Inhibitor, (+)-JQ1

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842570

Background: Cell-permeable. A potent and highly specific inhibitor for the BET (bromodomain and extra-terminal) family of bromodomains. (+)-JQ1 binds to BRD4 bromodomains 1 and 2 with Kd values of ~ 50 and 90 nM, respectively. The binding is competitive with… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
Bromodomain Inhibitor, (+)-JQ1, Biochemical
Full Product Name
Bromodomain Inhibitor, (+)-JQ1
Product Synonym Names
t-Butyl-2-((6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate
Form/Format
Appearance: Off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
456.99
CAS Number
1268524-70-4
Structure Available?
Yes
Cell-Permeable?
Yes
MDL Number
MFCD19443648
PubChem CID
46907787
Solubility/Reconstitution Instructions
DMSO (10 mM)
SMILES
CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)OC(C)(C)C)C4=CC=C(C=C4)Cl)C
InChi
InChI=1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m0/s1
InChi Key
DNVXATUJJDPFDM-KRWDZBQOSA-N
Handling
Protect from air and moisture

Product Categories/Family for Bromodomain Inhibitor, (+)-JQ1 biochemical

Biochemicals; Enzyme Inhibitors; Methyltransferase Inhibitors and Epigenetics; Methyltransferase; Inhibitors and Biochemicals (A-Z)

Structure of Bromodomain Inhibitor, (+)-JQ1 biochemical

Bromodomain Inhibitor, (+)-JQ1 Biochemical – Cat# MBS842570

Other Notes

Small volumes of Bromodomain Inhibitor, (+)-JQ1 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Bromodomain Inhibitor, (+)-JQ1 purchase

MBS842570 is a biochemical targeting Bromodomain Inhibitor, (+)-JQ1.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000