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Leukadherin-1

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842583

Background: A novel small molecule agonist of integrin CD11b/CD18 (also known as Mac-1). LA1 increases the extent of CD11b/CD18-dependent cell adhesion of transfected cells and of primary human and mouse neutrophils, which results in decreased chemotaxis and… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Leukadherin-1, Biochemical
Full Product Name
Leukadherin-1
Product Synonym Names
4-(5-((3-Benzyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl)furan-2-yl)-benzoic acid; LA1
Form/Format
Appearance: Crystalline solid
Purity/Purification
>=97% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
421.49
CAS Number
344897-95-6
Structure Available?
Yes
Cell-Permeable?
Yes
PubChem CID
5342077
Solubility/Reconstitution Instructions
DMSO (10 mM)
SMILES
C1=CC=C(C=C1)CN2C(=O)C(=CC3=CC=C(O3)C4=CC=C(C=C4)C(=O)O)SC2=S
InChi
InChI=1S/C22H15NO4S2/c24-20-19(29-22(28)23(20)13-14-4-2-1-3-5-14)12-17-10-11-18(27-17)15-6-8-16(9-7-15)21(25)26/h1-12H,13H2,(H,25,26)/b19-12-
InChi Key
AEZGRQSLKVNPCI-UNOMPAQXSA-N
Handling
Protect from air and light

Product Categories/Family for Leukadherin-1 biochemical

Biochemicals; Activators/Inducers; Agonists; etc.; Integrin Agonists; Biochemicals (A-Z)

Structure of Leukadherin-1 biochemical

Leukadherin-1 Biochemical – Cat# MBS842583

Other Notes

Small volumes of Leukadherin-1 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Leukadherin-1 purchase

MBS842583 is a biochemical targeting Leukadherin-1.
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