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DNA methylation inhibitor, Dichlone

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842596

Background: Dichlone, a popular pesticide and fungicide, acts as a potent DNA methylation inhibitor (EC?? = 460 nM against Dnmt3A/3L catalytic complex). Dichlone efficiently reactivates YFP gene expression in a stable HEK293 cell line by promoter… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
DNA methylation inhibitor, Dichlone, Biochemical
Full Product Name
DNA methylation inhibitor, Dichlone
Product Synonym Names
2,3-Dichloro-1,4-naphthoquinone; Dichlon
Form/Format
Appearance: Yellow solid
Purity/Purification
>=95% by GC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
227.04
CAS Number
117-80-6
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD00001677
PubChem CID
8342
Solubility/Reconstitution Instructions
DMSO or EtOH
SMILES
C1=CC=C2C(=C1)C(=O)C(=C(C2=O)Cl)Cl
InChi
InChI=1S/C10H4Cl2O2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H
InChi Key
SVPKNMBRVBMTLB-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for DNA methylation inhibitor, Dichlone biochemical

Enzyme Inhibitors; Methyltransferase InhibitorsEnzyme Inhibitors; Enzyme Inhibitors (A-Z) Biochemicals; Enzyme Inhibitors; Methyltransferase InhibitorsBiochemicals; Enzyme Inhibitors; Enzyme Inhibitors (A-Z) Epigenetics; Writer Enzymes; DNA Methyltransfer

Structure of DNA methylation inhibitor, Dichlone biochemical

2,3-Dichloro-1,4-naphthoquinone DNA methylation inhibitor, Dichlone Biochemical – Cat# MBS842596

Other Notes

Small volumes of DNA methylation inhibitor, Dichlone biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DNA methylation inhibitor, Dichlone purchase

MBS842596 is a biochemical targeting DNA methylation inhibitor, Dichlone.
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