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Baricitinib phosphate

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842603

Background: Baricitinib phosphate is a selective JAK1 and JAK2 inhibitor with IC?? values of 5.9 nM and 5.7 nM, respectively. Baricitinib is ~70 and ~10-fold selective versus JAK3 and Tyk2, with no inhibition to c-Met and Chk2. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Baricitinib phosphate, Biochemical
Full Product Name
Baricitinib phosphate
Product Synonym Names
2-[1-Ethylsulfonyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile; phosphoric acid; NCB 028050;LY 3009104;INCB028050;LY3009104;LY-3009104;INCB-028050
Form/Format
Appearance: Pale yellow to yellow solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
469.41
CAS Number
1187595-84-1
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
44231848
Solubility/Reconstitution Instructions
DMSO (~ 1 mg/ml)
SMILES
CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O
InChi
InChI=1S/C16H17N7O2S.H3O4P/c1-2-26(24,25)22-9-16(10-22,4-5-17)23-8-12(7-21-23)14-13-3-6-18-15(13)20-11-19-14;1-5(2,3)4/h3,6-8,11H,2,4,9-10H2,1H3,(H,18,19,20);(H3,1,2,3,4)
InChi Key
FBPOWTFFUBBKBB-UHFFFAOYSA-N
Handling
Protect from air and moisture

Product Categories/Family for Baricitinib phosphate biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; JAK InhibitorsEnzyme Inhibitors; Enzyme Inhibitors (A-Z) Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; JAK InhibitorsBiochemicals; Enzyme Inhibitors; Enzyme Inhibitors (A-Z) Epigenetics; Writer E

Structure of Baricitinib phosphate biochemical

Baricitinib Phosphate Biochemical – Cat# MBS842603

Other Notes

Small volumes of Baricitinib phosphate biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Baricitinib phosphate purchase

MBS842603 is a biochemical targeting Baricitinib phosphate.
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