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(+)-JQ1 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS385195

MBS385195 is an inhibitor targeting (+)-JQ1. (+)-JQ1 is a potent, high affinity, selective BET bromodomain inhibitor. More details

$155 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
(+)-JQ1, Inhibitor
Full Product Name
(+)-JQ1
Form/Format
Powder
Purity/Purification
>98%
Concentration
0.1 mM: 21.88 mL (1 mg); 109.41 mL (5 mg); 218.82mL (10 mg)
0.5 mM: 4.38 mL (1 mg); 21.88 mL (5 mg); 43.76 mL (10 mg)
1 mM: 2.19 mL (1 mg); 10.94 mL (5 mg); 21.88 mL (10 mg)
5 mM: 0.44 mL (1 mg); 2.19 mL (5 mg); 4.38 mL (10 mg) (lot specific)
Preparation and Storage
at -20 degree C 3 years Powder
Molecular Weight
456.99
CAS Number
1268524-70-4
Formula
C23H25ClN4O2S
SMILES
CC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)OC(C)(C)C)C4=CC=C(C=C4)Cl)C
Actions
Inhibitor
Solubility (DMSO)
91 mg/mL (199.12 mM)
Solubility (Ethanol)
91 mg/mL (199.12 mM)
Solubility (Water)
<1 mg/mL (<1 mM)
Availability
We cannot ship this item to Switzerland, Italy, Germany, France and Austria.

Chemical Structure of (+)-JQ1, inhibitor

(+)-JQ1 Inhibitor – Cat# MBS385195

Product References and Citations for (+)-JQ1, inhibitor

A Carrer, .et al. Acetyl-CoA metabolism supports multi-step pancreatic tumorigenesis, Cancer Discov, 2019, Jan 9. pii: CD-18-0567 PMID: 30626590
Clocchiatti A, .et al. Androgen receptor functions as transcriptional repressor of cancer-associated fibroblast activation, J Clin Invest, 2018, Dec 3;128(12):5531-5548 PMID: 30395538

Other Notes

Small volumes of (+)-JQ1, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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