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A 83-01

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842636

Background: A selective inhibitor of TGF-beta type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC?? values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF-beta-induced… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
A 83-01, Biochemical
Full Product Name
A 83-01
Product Gene Name
A 83-01 biochemical
Product Synonym Names
3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-p yrazole-1-carbothioamide
Form/Format
Appearance: Pale yellow solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
421.52
CAS Number
909910-43-6
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD08705403
PubChem CID
16218924
Solubility/Reconstitution Instructions
DMSO
SMILES
CC1=CC=CC(=N1)C2=NN(C=C2C3=CC=NC4=CC=CC=C34)C(=S)NC5=CC=CC=C5
InChi
InChI=1S/C25H19N5S/c1-17-8-7-13-23(27-17)24-21(19-14-15-26-22-12-6-5-11-20(19)22)16-30(29-24)25(31)28-18-9-3-2-4-10-18/h2-16H,1H3,(H,28,31)
InChi Key
HIJMSZGHKQPPJS-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for A 83-01 biochemical

Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase Inhibitors and Biochemicals; Biochemicals (A-Z)

Structure of A 83-01 biochemical

A 83-01 Biochemical – Cat# MBS842636

Other Notes

Small volumes of A 83-01 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for A 83-01 purchase

MBS842636 is a biochemical targeting A 83-01.
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