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Celastrol

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842657

Background: Cell-permeable. An Antioxidant, anti-inflammatory and immunosuppressive agent. Suppresses LPS-induced cytokine release in macrophages and monocytes (IC?? = 40 nM for IL-1beta and IL-1alpha, 80 nM for IL-6, 110 nM for prostaglandin E2 and 210 nM… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Celastrol, Biochemical
Full Product Name
Celastrol
Product Synonym Names
(9beta,13alpha,14beta,20alpha)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid
Form/Format
Appearance: Red solid
Purity/Purification
>=98% by TLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
450.61
CAS Number
34157-83-0
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD03424073
PubChem CID
122724
Solubility/Reconstitution Instructions
DMSO (45 mg/ml) or Ethanol (30 mg/ml)
SMILES
CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C)O
InChi
InChI=1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,31H,9-14,16H2,1-6H3,(H,32,33)/t22-,25-,26-,27+,28-,29+/m1/s1
InChi Key
KQJSQWZMSAGSHN-JJWQIEBTSA-N
Handling
Protect from air and moisture

Product Categories/Family for Celastrol biochemical

Biochemicals; Antioxidants and Enzyme Inhibitors; NF-KB Pathway Inhibitors and Enzyme Inhibitors; Proteasome Inhibitors and Biochemicals (A-Z)

Structure of Celastrol biochemical

Celastrol Biochemical – Cat# MBS842657

Other Notes

Small volumes of Celastrol biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Celastrol purchase

MBS842657 is a biochemical targeting Celastrol.
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