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CAL-101 (GS-1101)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842674

Background: CAL-101 is a cell-permeable inhibitor of the PI3K catalytic subunit p110delta (IC?? = 2.5 nM) that displays 40- to 300-fold selectivity against other PI3K class I enzymes (IC??s = 820, 565, and 89 nM for p110alpha, beta, and gamma,… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CAL-101 (GS-1101), Biochemical
Full Product Name
CAL-101 (GS-1101)
Product Synonym Names
5-fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone; Idealisib
Form/Format
Appearance: White solid
Purity/Purification
>98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
415.42
CAS Number
870281-82-6
Structure Available?
Y
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
11625818
Solubility/Reconstitution Instructions
DMSO(~ 25 mg/ml) or EtOH (~ 15 mg/ml)
SMILES
CCC(C1=NC2=C(C(=CC=C2)F)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5
InChi
InChI=1S/C22H18FN7O/c1-2-15(28-20-18-19(25-11-24-18)26-12-27-20)21-29-16-10-6-9-14(23)17(16)22(31)30(21)13-7-4-3-5-8-13/h3-12,15H,2H2,1H3,(H2,24,25,26,27,28)/t15-/m0/s1
InChi Key
 IFSDAJWBUCMOAH-HNNXBMFYSA-N
Handling
Protect from air and light

Product Categories/Family for CAL-101 (GS-1101) biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; PI 3-Kinase Inhibitors and Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; PI 3-Kinase Inhibitors and Signaling Pathways; PI3 K/Akt/mTOR Signaling; Inhibitors; PI 3-K Inhibitors and Biochemicals; B

Structure of CAL-101 (GS-1101) biochemical

CAL-101 (GS-1101) Biochemical – Cat# MBS842674

Other Notes

Small volumes of CAL-101 (GS-1101) biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CAL-101 (GS-1101) purchase

MBS842674 is a biochemical targeting CAL-101 (GS-1101).
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