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BIIB 021

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842688

Background: A synthetic, small molecule Hsp90 inhibitor that binds competitively with geldanamycin in the ATP-binding pocket of Hsp90. In tumor cells, BIIB021 induces the degradation of Hsp90 client proteins including HER-2, AKT, and Raf-1 and up-regulates… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
BIIB 021, Biochemical
Full Product Name
BIIB 021
Product Gene Name
BIIB 021 biochemical
Product Synonym Names
6-Chloro-9-[(4-methoxy-3,5-dimethyl--2-pyridinyl)methyl]-9H-purin-2-amine; CNF2024
Form/Format
Appearance: White to off-white solid
Purity/Purification
>=99% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
318.76
CAS Number
848695-25-0
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD15528939
PubChem CID
16736529
Solubility/Reconstitution Instructions
DMSO (~65 mg/ml) or EtOH (~3 mg/ml)
SMILES
CC1=CN=C(C(=C1OC)C)CN2C=NC3=C2N=C(N=C3Cl)N
InChi
InChI=1S/C14H15ClN6O/c1-7-4-17-9(8(2)11(7)22-3)5-21-6-18-10-12(15)19-14(16)20-13(10)21/h4,6H,5H2,1-3H3,(H2,16,19,20)
InChi Key
QULDDKSCVCJTPV-UHFFFAOYSA-N
Handling
Protect from light and moisture

Product Categories/Family for BIIB 021 biochemical

Enzyme Inhibitors; Heat Shock Protein (Hsp) Inhibitors and Biochemicals; Enzyme Inhibitors; Heat Shock Protein (Hsp) Inhibitors and Biochemicals (A-Z)

Structure of BIIB 021 biochemical

BIIB 021 Biochemical – Cat# MBS842688

Other Notes

Small volumes of BIIB 021 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BIIB 021 purchase

MBS842688 is a biochemical targeting BIIB 021.
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