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3-Deazaneplanocin A (DZNep)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842691

Background: A lysine methyltransferase EZH2 (KMT63) inhibitor. DZNep is a selective inhibitor of trimethylation of lysine 27 on histone H3 (H3K27me3) and lysine 20 on histone H4 (H4K20me3). DZNep treatment of cultured human AML cells induces increased… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
3-Deazaneplanocin A, Biochemical
Full Product Name
3-Deazaneplanocin A
Product Synonym Names
DZNep; NSC 617989; 5R-(4-amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1S,2R-diol
Form/Format
Appearance: Off-white solid
Purity/Purification
>=98%
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
262.26
CAS Number
102052-95-9
Structure Available?
Yes
Cell-Permeable?
Yes
MDL Number
MFCD12545899
PubChem CID
73087
Solubility/Reconstitution Instructions
DMSO (20 mg/ml) or EtOH (1 mg/ml)
SMILES
C1=CN=C(C2=C1N(C=N2)C3C=C(C(C3O)O)CO)N
InChi
InChI=1S/C12H14N4O3/c13-12-9-7(1-2-14-12)16(5-15-9)8-3-6(4-17)10(18)11(8)19/h1-3,5,8,10-11,17-19H,4H2,(H2,13,14)/t8-,10-,11+/m1/s1
InChi Key
OMKHWTRUYNAGFG-IEBDPFPHSA-N
Handling
Protect from air and light

Product Categories/Family for 3-Deazaneplanocin A biochemical

Biochemicals; Enzyme Inhibitors; Methyltransferase Inhibitors and Epigenetics; Methyltransferase; Inhibitors and Biochemicals (A-Z)

Structure of 3-Deazaneplanocin A biochemical

3-Deazaneplanocin A DZNep Biochemical – Cat# MBS842691

Other Notes

Small volumes of 3-Deazaneplanocin A biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 3-Deazaneplanocin A purchase

MBS842691 is a biochemical targeting 3-Deazaneplanocin A.
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