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Lactacystin (Synthetic)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842709

Background: Cell-permeable. A potent and selective inhibitor of the 20 S proteasome. Binds irreversibly to the active site N-terminal threonine residue of the catalytic beta-subunit of the 20S proteasome, thereby inhibiting its chymotrypsin and trypsin-like… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Lactacystin, Biochemical
Full Product Name
Lactacystin (Synthetic)
Product Synonym Names
2-(acetylamino)-3-[({3-hydroxy-2-[1-hydroxy-2-methylpropyl]-4-methyl-5-oxopyrrolidin-2-yl}carbonyl)sulfanyl]propanoic acid
Form/Format
Appearance: White solid
Purity/Purification
>=95% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
376.42
CAS Number
133343-34-7
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD01076525
PubChem CID
3870
Solubility/Reconstitution Instructions
DMSO (25 mg/ml)
SMILES
CC1C(C(NC1=O)(C(C(C)C)O)C(=O)SCC(C(=O)O)NC(=O)C)O
InChi
InChI=1S/C15H24N2O7S/c1-6(2)10(19)15(11(20)7(3)12(21)17-15)14(24)25-5-9(13(22)23)16-8(4)18/h6-7,9-11,19-20H,5H2,1-4H3,(H,16,18)(H,17,21)(H,22,23)
InChi Key
DAQAKHDKYAWHCG-UHFFFAOYSA-N
Handling
Protect from air and moisture

Other Notes

Small volumes of Lactacystin biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Lactacystin purchase

MBS842709 is a biochemical targeting Lactacystin. Also known as Lactacystin (Synthetic).
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