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Akt Inhibitor, Isozyme-Selective

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842710

Background: Cell-permeable. A potent and selective inhibitor of Akt1/Akt2 activity (IC?? = 58 nM (Akt1), 210 nM (Akt2) and 2.12 uM (Akt3) in in vitro kinase assays). The inhibition appears to be pleckstrin homology (PH) domain-dependent. It does not exhibit… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Akt Inhibitor, Isozyme-Selective, Biochemical
Full Product Name
Akt Inhibitor, Isozyme-Selective
Product Synonym Names
1,3-Dihydro-1-(1-((4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one; Akti-1/2
Form/Format
Appearance: Light yellow solid
Purity/Purification
>=97% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
551.65
CAS Number
612847-09-3
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD08705407
PubChem CID
10196499
Solubility/Reconstitution Instructions
DMSO
SMILES
C1CN(CCC1N2C3=CC=CC=C3NC2=O)CC4=CC=C(C=C4)C5=NC6=CC7=C(C=C6N=C5C8=CC=CC=C8)N=CN7
InChi
InChI=1S/C34H29N7O/c42-34-39-26-8-4-5-9-31(26)41(34)25-14-16-40(17-15-25)20-22-10-12-24(13-11-22)33-32(23-6-2-1-3-7-23)37-29-18-27-28(36-21-35-27)19-30(29)38-33/h1-13,18-19,21,25H,14-17,20H2,(H,35,36)(H,39,42)
InChi Key
BIWGYFZAEWGBAL-UHFFFAOYSA-N
Handling
Protect from air and moisture

Other Notes

Small volumes of Akt Inhibitor, Isozyme-Selective biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS842710 is a biochemical targeting Akt Inhibitor, Isozyme-Selective.
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