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Chaetocin

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842763

Background: A fungal mycotoxin that inhibits the histone lysine methyltransferase (HKMT) SU(VAR)3-9 (IC?? = 0.8 muM). Inhibits other Lys9-specific HMTs, including G9a (IC?? = 2.5 muM) and DIM5 (IC?? = 3 muM). Selectivity for Lys9-HMTs is indicated by higher… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Chaetocin, Biochemical
Full Product Name
Chaetocin
Product Synonym Names
(3S,3'S,5aR,5aR,10bR,10'bR,11aS,11'aS)--2,2',3,3',5a,5'a,6,6'-octahydro-3,3'-bis(hydroxymethyl-)-2,2'-dimethyl-[10b,10'b(11H,11'H)-bi3,11a-epidithio--11aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole]-1,1',4-,4'-tetrone
Form/Format
Appearance: Off-white solid
Purity/Purification
>=95%
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
696.84
CAS Number
28097-03-2
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD00133163
PubChem CID
161591
Solubility/Reconstitution Instructions
DMSO (~7 mg/ml)
SMILES
CN1C(=O)C23CC4(C(N2C(=O)C1(SS3)CO)NC5=CC=CC=C54)C67CC89C(=O)N(C(C(=O)N8C6NC1=CC=CC=C71)(SS9)CO)C
InChi
InChI=1S/C30H28N6O6S4/c1-33-21(39)27-11-25(15-7-3-5-9-17(15)31-19(25)35(27)23(41)29(33,13-37)45-43-27)26-12-28-22(40)34(2)30(14-38,46-44-28)24(42)36(28)20(26)32-18-10-6-4-8-16(18)26/h3-10,19-20,31-32,37-38H,11-14H2,1-2H3
InChi Key
PZPPOCZWRGNKIR-UHFFFAOYSA-N
Handling
Protect from light and moisture

Product Categories/Family for Chaetocin biochemical

Enzyme Inhibitors; Methyltransferase Inhibitors and Biochemicals; Enzyme Inhibitors; Methyltransferase Inhibitors and Biochemicals (A-Z)

Structure of Chaetocin biochemical

Chaetocin Biochemical – Cat# MBS842763

Other Notes

Small volumes of Chaetocin biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Chaetocin purchase

MBS842763 is a biochemical targeting Chaetocin.
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