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Quizartinib (AC220)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842816

Background: Cell-permeable. A second generation FLT3 receptor tyrosine kinase inhibitor. Quizartinib displays high affinity for FLT3 in a binding assay (Kd = 1.6 nM) and is a potent inhibitor in cellular autophosphorylation assays (IC?? = 1.1 nM for FLT3-ITD… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Quizartinib, Biochemical
Full Product Name
Quizartinib
Product Synonym Names
AC220; AC010220
Form/Format
Appearance: Off-white solid
Purity/Purification
>=99% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
560.67
CAS Number
950769-58-1
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD18074524
PubChem CID
24889392
Solubility/Reconstitution Instructions
DMSO (~200 mg/ml)
SMILES
CC(C)(C)C1=CC(=NO1)NC(=O)NC2=CC=C(C=C2)C3=CN4C5=C(C=C(C=C5)OCCN6CCOCC6)SC4=N3
InChi
InChI=1S/C29H32N6O4S/c1-29(2,3)25-17-26(33-39-25)32-27(36)30-20-6-4-19(5-7-20)22-18-35-23-9-8-21(16-24(23)40-28(35)31-22)38-15-12-34-10-13-37-14-11-34/h4-9,16-18H,10-15H2,1-3H3,(H2,30,32,33,36)
InChi Key
CVWXJKQAOSCOAB-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for Quizartinib biochemical

Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase Inhibitors and Biochemicals (A-Z)

Structure of Quizartinib biochemical

Quizartinib AC220 Biochemical – Cat# MBS842816

Other Notes

Small volumes of Quizartinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Quizartinib purchase

MBS842816 is a biochemical targeting Quizartinib.
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