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NVP-BGJ398

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842837

Background: NVP-BGJ398 is a potent and selective, pan-FGFR kinase inhibitor. It inhibits the proliferation of various FGFR-dependent cell lines at nano-molar concentrations including breast and lung cancers harboring FGFR1 amplification, FGFR2-amplified… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
NVP-BGJ398, Biochemical
Full Product Name
NVP-BGJ398
Product Gene Name
NVP-BGJ398 biochemical
Product Synonym Names
3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea
Form/Format
Appearance: White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
560.49
CAS Number
872511-34-7
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
53235510
Solubility/Reconstitution Instructions
DMSO
SMILES
CCN1CCN(CC1)C2=CC=C(C=C2)NC3=CC(=NC=N3)N(C)C(=O)NC4=C(C(=CC(=C4Cl)OC)OC)Cl
InChi
InChI=1S/C26H31Cl2N7O3/c1-5-34-10-12-35(13-11-34)18-8-6-17(7-9-18)31-21-15-22(30-16-29-21)33(2)26(36)32-25-23(27)19(37-3)14-20(38-4)24(25)28/h6-9,14-16H,5,10-13H2,1-4H3,(H,32,36)(H,29,30,31)
InChi Key
QADPYRIHXKWUSV-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for NVP-BGJ398 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase InhibitorsEnzyme Inhibitors; Enzyme Inhibitors (A-Z) Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase InhibitorsBiochemicals; Enzyme Inhibitors; Enzym

Structure of NVP-BGJ398 biochemical

NVP-BGJ398 Biochemical – Cat# MBS842837

Other Notes

Small volumes of NVP-BGJ398 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NVP-BGJ398 purchase

MBS842837 is a biochemical targeting NVP-BGJ398.
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