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IWP-2

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842838

Background: Cell-permeable. Acts as an inhibitor of Wnt secretion and processing. It blocks Wnt-dependent signaling (IC?? = 27 nM) by inhibition of the O-acyltransferase Porcn. Porcn is a member of the membrane-bound O-acyltransferase (MBOAT) family, which… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
IWP-2, Biochemical
Full Product Name
IWP-2
Product Gene Name
IWP-2 biochemical
Product Synonym Names
N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide
Form/Format
Appearance: Beige solid
Purity/Purification
>=98% by TLC
Preparation and Storage
At -20 degree C
Shelf Life: 48 months
Molecular Weight
466.6
CAS Number
686770-61-6
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD04457599
PubChem CID
2155128
Solubility/Reconstitution Instructions
DMSO (~5 mg/ml with warming)
SMILES
CC1=CC2=C(C=C1)N=C(S2)NC(=O)CSC3=NC4=C(C(=O)N3C5=CC=CC=C5)SCC4
InChi
InChI=1S/C22H18N4O2S3/c1-13-7-8-15-17(11-13)31-21(23-15)25-18(27)12-30-22-24-16-9-10-29-19(16)20(28)26(22)14-5-3-2-4-6-14/h2-8,11H,9-10,12H2,1H3,(H,23,25,27)
InChi Key
WRKPZSMRWPJJDH-UHFFFAOYSA-N
Handling
Protect from light and air

Product Categories/Family for IWP-2 biochemical

Biochemicals; Enzyme Inhibitors; Wnt Signaling Inhibitors and Diabetes; Obesity & Metabolic Syndrome; Signaling Pathways in Diabetes and Obesity; GSK-3/Wnt Signaling; Wnt/b-Catenin Signaling Pathway Modulators and Biochemicals (A-Z)

Structure of IWP-2 biochemical

IWP-2 Biochemical – Cat# MBS842838

Other Notes

Small volumes of IWP-2 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IWP-2 purchase

MBS842838 is a biochemical targeting IWP-2.
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