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SIRT2 Inhibitor, B2

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842876

Background: Cell-permeable. A Sirtuin 2 (SIRT2) inhibitor (IC50 = 35 uM). Promotes inclusion formation in cellular models of both Huntington's disease and Parkinson's disease. Prevents huntingtin-mediated proteasome dysfunction and reduces… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
SIRT2 Inhibitor, B2, Biochemical
Full Product Name
SIRT2 Inhibitor, B2
Product Synonym Names
5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline; CPNQ
Form/Format
Appearance: Yellow solid
Purity/Purification
>=95%
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
396.83
CAS Number
115687-05-3
Structure Available?
Yes
Cell-Permeable?
Yes
MDL Number
MFCD02039810
PubChem CID
3953303
Solubility/Reconstitution Instructions
DMSO (>5 mg/ml)
SMILES
C1CN(CCN1C2=C3C=CC=NC3=C(C=C2)[N+](=O)[O-])C(=O)C4=CC=C(C=C4)Cl
InChi
InChI=1S/C20H17ClN4O3/c21-15-5-3-14(4-6-15)20(26)24-12-10-23(11-13-24)17-7-8-18(25(27)28)19-16(17)2-1-9-22-19/h1-9H,10-13H2
InChi Key
KLNPVNZJCWIQSK-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for SIRT2 Inhibitor, B2 biochemical

Biochemicals; Enzyme Inhibitors; SIRT Inhibitors Epigenetics; SIRTs; SIRT Inhibitors and Biochemicals (A-Z)

Structure of SIRT2 Inhibitor, B2 biochemical

SIRT2 Inhibitor, B2 Biochemical – Cat# MBS842876

Other Notes

Small volumes of SIRT2 Inhibitor, B2 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SIRT2 Inhibitor, B2 purchase

MBS842876 is a biochemical targeting SIRT2 Inhibitor, B2.
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