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PIK-294

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842899

Background: PIK-294 is a highly potent and selective p110delta inhibitor (IC?? of 10 nM). Displays 1000-, 49- and 16-fold less potency against PI3Kalpha/beta/gamma, respectively. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PIK-294, Biochemical
Full Product Name
PIK-294
Product Gene Name
PIK-294 biochemical
Product Synonym Names
2-[[4-Amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone
Form/Format
Appearance: Crystalline solid
Purity/Purification
>98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
489.53
CAS Number
900185-02-6
Structure Available?
Y
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
24905149
Solubility/Reconstitution Instructions
DMSO (>60 mg/ml)
SMILES
O=C1N(C2=CC=CC=C2C)C(CN3N=C(C4=CC=CC(O)=C4)C5=C(N)N=CN=C53)=NC6=C1C(C)=CC=C6
InChi
InChI=1S/C28H23N7O2/c1-16-7-3-4-12-21(16)35-22(32-20-11-5-8-17(2)23(20)28(35)37)14-34-27-24(26(29)30-15-31-27)25(33-34)18-9-6-10-19(36)13-18/h3-13,15,36H,14H2,1-2H3,(H2,29,30,31)
InChi Key
WFSLJOPRIJSOJR-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for PIK-294 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; PI 3-Kinase Inhibitors and Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; PI 3-Kinase Inhibitors and Signaling Pathways; PI3 K/Akt/mTOR Signaling; Inhibitors; PI 3-K Inhibitors and Biochemicals; B

Structure of PIK-294 biochemical

PIK-294 Biochemical – Cat# MBS842899

Other Notes

Small volumes of PIK-294 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PIK-294 purchase

MBS842899 is a biochemical targeting PIK-294.
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