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Tipifarnib, Free base

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842913

Background: A potent, selective, nonpeptidomimetic inhibitor of farnesyl protein transferase (FPT), an enzyme involved in protein processing (farnesylation) for signal transduction. Displays significant antitumor effects in vivo.  Tipifarnib competitively… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Tipifarnib, Biochemical
Full Product Name
Tipifarnib, Free base
Product Synonym Names
(R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one; R-115777
Form/Format
Appearance: White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
489.4
CAS Number
192185-72-1
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD09837802
PubChem CID
159324
Solubility/Reconstitution Instructions
DMSO (~ 15 mg/ml) or Ethanol (~ 10 mg/ml)
SMILES
CN1C=NC=C1C(C2=CC=C(C=C2)Cl)(C3=CC4=C(C=C3)N(C(=O)C=C4C5=CC(=CC=C5)Cl)C)N
InChi
InChI=1S/C27H22Cl2N4O/c1-32-16-31-15-25(32)27(30,18-6-9-20(28)10-7-18)19-8-11-24-23(13-19)22(14-26(34)33(24)2)17-4-3-5-21(29)12-17/h3-16H,30H2,1-2H3/t27-/m1/s1
InChi Key
PLHJCIYEEKOWNM-HHHXNRCGSA-N
Handling
Protect from air and light

Product Categories/Family for Tipifarnib biochemical

Enzyme Inhibitors; Farnesyl Protein Transferase (FPT) Inhibitors and Biochemicals; Enzyme Inhibitors; Farnesyl Protein Transferase (FPT) Inhibitors and Biochemicals; Biochemicals (A-Z)

Structure of Tipifarnib biochemical

Tipifarnib, Free base Biochemical – Cat# MBS842913

Other Notes

Small volumes of Tipifarnib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Tipifarnib purchase

MBS842913 is a biochemical targeting Tipifarnib. Also known as Tipifarnib, Free base.
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