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XAV939

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842914

Background: A Tankyrase (TNKS) inhibitor (IC?? = 110 nM for TNKS1 and 4 nM for TNKS2). Antagonizes wnt signaling via stimulation of beta-catenin degradation and stabilization of axin. Inhibits proliferation of the mu-catenin-dependent colon carcinoma cell… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
XAV939, Biochemical
Full Product Name
XAV939
Product Gene Name
XAV939 biochemical
Product Synonym Names
3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thi opyrano[4,3-d]pyrimidin-4-one
Form/Format
Appearance: White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
312.31
CAS Number
284028-89-3
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD16879017
PubChem CID
2726824
Solubility/Reconstitution Instructions
DMSO (50 mM)
SMILES
C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
InChi
InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20)
InChi Key
KLGQSVMIPOVQAX-UHFFFAOYSA-N
Handling
Protect from air and light

Product Categories/Family for XAV939 biochemical

Biochemicals; Enzyme Inhibitors; Other Inhibitors and; Biochemicals; Biochemicals (A-Z)

Structure of XAV939 biochemical

XAV939 Biochemical – Cat# MBS842914

Other Notes

Small volumes of XAV939 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for XAV939 purchase

MBS842914 is a biochemical targeting XAV939.
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