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BI 6727 (Volasertib)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842922

Background: A highly potent, selective and ATP-competitive inhibitor of polo-like kinases 1, 2 and 3 (PLK1, 2 and 3), with IC??s at 0.87, 5 and 56 nM, respectively.  More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
BI 6727, Biochemical
Full Product Name
BI 6727
Product Gene Name
BI 6727 biochemical
Product Synonym Names
Volasertib
Form/Format
Appearance: White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
618.81
CAS Number
755038-65-4
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD20926414
PubChem CID
10461508
Solubility/Reconstitution Instructions
DMSO
SMILES
CCC1C(=O)N(C2=CN=C(N=C2N1C(C)C)NC3=C(C=C(C=C3)C(=O)NC4CCC(CC4)N5CCN(CC5)CC6CC6)OC)C
InChi
InChI=1S/C34H50N8O3/c1-6-28-33(44)39(4)29-20-35-34(38-31(29)42(28)22(2)3)37-27-14-9-24(19-30(27)45-5)32(43)36-25-10-12-26(13-11-25)41-17-15-40(16-18-41)21-23-7-8-23/h9,14,19-20,22-23,25-26,28H,6-8,10-13,15-18,21H2,1-5H3,(H,36,43)(H,35,37,38)/t25?,26?,28-/m1/s1
InChi Key
SXNJFOWDRLKDSF-XKHVUIRMSA-N
Handling
Protect from light and moisture

Product Categories/Family for BI 6727 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Polo Like Kinase (PLK) Inhibitors and Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Polo Like Kinase (PLK) Inhibitors and Biochemicals (A-Z)

Structure of BI 6727 biochemical

BI 6727 Volasertib Biochemical – Cat# MBS842922

Other Notes

Small volumes of BI 6727 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BI 6727 purchase

MBS842922 is a biochemical targeting BI 6727.
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