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CEP-18770

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842925

Background: CEP-18770 is a reversible P2 threonine boronic acid inhibitor of the chymotrypsin-like activity of the proteasome. Displays anti-multimyeloma (MM) effect. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CEP-18770, Biochemical
Full Product Name
CEP-18770
Product Gene Name
CEP-18770 biochemical
Product Synonym Names
[(1R)-1-[[(2S,3R)-3-Hydroxy-2-[[(6-phenylpyridin-2-yl)carbonyl]amino]-1-oxobutyl]amino]-3-methylbutyl]boronic acid
Form/Format
Appearance: Off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
413.28
CAS Number
847499-27-8
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
24800541
Solubility/Reconstitution Instructions
DMSO (>70 mg/ml) or EtOH (>70 mg/ml)
SMILES
B(C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C1=CC=CC(=N1)C2=CC=CC=C2)(O)O
InChi
InChI=1S/C21H28BN3O5/c1-13(2)12-18(22(29)30)24-21(28)19(14(3)26)25-20(27)17-11-7-10-16(23-17)15-8-5-4-6-9-15/h4-11,13-14,18-19,26,29-30H,12H2,1-3H3,(H,24,28)(H,25,27)/t14-,18+,19+/m1/s1
InChi Key
SJFBTAPEPRWNKH-CCKFTAQKSA-N
Handling
Protect from air and mositure

Product Categories/Family for CEP-18770 biochemical

Enzyme Inhibitors; Proteasome Inhibitors and Enzyme Inhibitors; Ubiquitin Proteasome Pathway Inhibitors and Biochemicals; Enzyme Inhibitors; Proteasome Inhibitors and Biochemicals; Enzyme Inhibitors; Ubiquitin Proteasome Pathway Inhibitors and Biochemical

Structure of CEP-18770 biochemical

CEP-18770 Biochemical – Cat# MBS842925

Other Notes

Small volumes of CEP-18770 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CEP-18770 purchase

MBS842925 is a biochemical targeting CEP-18770.
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