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PYR-41

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842942

Background: Cell-permeable. An irreversible ubiquitin-activating enzyme (E1) inhibitor (IC?? < 10 muM). Blocks ubiquitylation and prevents ubiquitin-mediated proteasomal degradation. Inhibits NF-kappaB activation, blocks degradation of p53, increases p21… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PYR-41, Biochemical
Full Product Name
PYR-41
Product Gene Name
PYR-41 biochemical
Product Synonym Names
4-[4-[(5-Nitro-2-furanyl)methylene]-3,5-dioxo-1-pyrazolidinyl]benzoic acid ethyl ester
Form/Format
Appearance: Brown solid
Purity/Purification
>=98% by TLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
371.3
CAS Number
418805-02-4
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
5335621
Solubility/Reconstitution Instructions
DMSO (~25 mg/ml)
SMILES
CCOC(=O)C1=CC=C(C=C1)N2C(=O)C(=CC3=CC=C(O3)[N+](=O)[O-])C(=O)N2
InChi
InChI=1S/C17H13N3O7/c1-2-26-17(23)10-3-5-11(6-4-10)19-16(22)13(15(21)18-19)9-12-7-8-14(27-12)20(24)25/h3-9H,2H2,1H3,(H,18,21)/b13-9-
InChi Key
ARGIPZKQJGFSGQ-LCYFTJDESA-N
Handling
Protect from light and air

Product Categories/Family for PYR-41 biochemical

Biochemicals; Enzyme Inhibitors; Ubiquitin Activating Enzyme E1 Inhibitor and Biochemicals (A-Z)

Structure of PYR-41 biochemical

PYR-41 Biochemical – Cat# MBS842942

Other Notes

Small volumes of PYR-41 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PYR-41 purchase

MBS842942 is a biochemical targeting PYR-41.
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