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A77 1726

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842963

Background: Physiologically active metabolite of the immunosuppressive drug leflunomide. Inhibits the activity of dihydrorotate dehydrogenase and of protein tyrosine kinases. Blocks TNF-mediated NF-kappaB activation in a dose- and time-dependent manner. Also… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
A77 1726, Biochemical
Full Product Name
A77 1726
Product Gene Name
A77 1726 biochemical
Product Synonym Names
N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide; 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide
Form/Format
Appearance: White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 48 months
Molecular Weight
270.21
CAS Number
108605-62-5
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD00910058
PubChem CID
54684141
Solubility/Reconstitution Instructions
DMSO
SMILES
CC(=C(C#N)C(=O)NC1=CC=C(C=C1)C(F)(F)F)O
InChi
InChI=1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7-
InChi Key
UTNUDOFZCWSZMS-YFHOEESVSA-N
Handling
Protect from light and air

Product Categories/Family for A77 1726 biochemical

Biochemicals; Immunosuppressants and Biochemicals (A-Z)

Structure of A77 1726 biochemical

A77 1726 Biochemical – Cat# MBS842963

Other Notes

Small volumes of A77 1726 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for A77 1726 purchase

MBS842963 is a biochemical targeting A77 1726.
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