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GSK-3beta Inhibitor, TWS119

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842975

Background: A potent inhibitor of GSK-3beta (Glycogen synthase kinase-3beta) (IC?? = 30 nM). At 400 nM, TWS119 induces neurogenesis in murine embryonic stem cells making it a useful tool to regulate stem cell self-renewal and differentiation. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GSK-3beta Inhibitor, TWS119, Biochemical
Full Product Name
GSK-3beta Inhibitor, TWS119
Product Synonym Names
3-[[6-(3-Aminophenyl)-1H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-phenol
Form/Format
Appearance: Slightly pink solid
Purity/Purification
>=95% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
318.33
CAS Number
601514-19-6
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
MDL Number
MFCD09037535
PubChem CID
9549289
Solubility/Reconstitution Instructions
DMSO (20 mg/ml)
SMILES
C1=CC(=CC(=C1)N)C2=CC3=C(N2)N=CN=C3OC4=CC=CC(=C4)O
InChi
InChI=1S/C18H14N4O2/c19-12-4-1-3-11(7-12)16-9-15-17(22-16)20-10-21-18(15)24-14-6-2-5-13(23)8-14/h1-10,23H,19H2,(H,20,21,22)
InChi Key
VPVLEBIVXZSOMQ-UHFFFAOYSA-N
Handling
Protect from air and light

Structure of GSK-3beta Inhibitor, TWS119 biochemical

GSK-3beta Inhibitor, TWS119 Biochemical – Cat# MBS842975

Other Notes

Small volumes of GSK-3beta Inhibitor, TWS119 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS842975 is a biochemical targeting GSK-3beta Inhibitor, TWS119.
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