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Rottlerin

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS842982

Background: Originally reported as an inhibitor of Protein Kinase C isoforms with selectivity for PKCdelta. However, more recent studies have shown Rottlerin did not block PKCdelta activity but did block other kinase and non-kinase proteins in vitro and… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Rottlerin, Biochemical
Full Product Name
Rottlerin
Product Synonym Names
3'-[(8-Cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)methyl]-2',4',6'-trihydroxy-5'-methylacetophenone; Mallotoxin
Form/Format
Appearance: Orange to brown solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Molecular Weight
516.55
CAS Number
82-08-6
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
No
MDL Number
MFCD00017361
PubChem CID
5281847
Solubility/Reconstitution Instructions
DMSO (30 mg/ml) or Ethanol (1 mg/ml)
SMILES
CC1=C(C(=C(C(=C1O)C(=O)C)O)CC2=C(C3=C(C(=C2O)C(=O)C=CC4=CC=CC=C4)OC(C=C3)(C)C)O)O
InChi
InChI=1S/C30H28O8/c1-15-24(33)19(27(36)22(16(2)31)25(15)34)14-20-26(35)18-12-13-30(3,4)38-29(18)23(28(20)37)21(32)11-10-17-8-6-5-7-9-17/h5-13,33-37H,14H2,1-4H3/b11-10+
InChi Key
DEZFNHCVIZBHBI-ZHACJKMWSA-N
Handling
Protect from air and light

Product Categories/Family for Rottlerin biochemical

Apoptosis; Autophagy; Autophagy Activators and Biochemicals (A-Z)

Structure of Rottlerin biochemical

Rottlerin Biochemical – Cat# MBS842982

Other Notes

Small volumes of Rottlerin biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Rottlerin purchase

MBS842982 is a biochemical targeting Rottlerin.
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