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EZSolution GW2580

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843003

Background: A small-molecule, ATP-competitive inhibitor of cFMS kinase; at 60 nM it inhibits human cFMS kinase completely in vitro and was inactive against 26 other kinases.  GW2580 also inhibits lipopolysaccharide (LPS)-induced TNF production in mice, but… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GW2580, Biochemical
Full Product Name
EZSolution GW2580
Product Gene Name
GW2580 biochemical
Product Synonym Names
5-(3-Methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine
Form/Format
A 10 mM solution in anhydrous DMSO
Appearance: Liquid
Purity/Purification
>=99% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Molecular Weight
366.41
CAS Number
870483-87-7
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
11617559
SMILES
COC1=CC=C(C=C1)COC2=C(C=C(C=C2)CC3=CN=C(N=C3N)N)OC
InChi
InChI=1S/C20H22N4O3/c1-25-16-6-3-13(4-7-16)12-27-17-8-5-14(10-18(17)26-2)9-15-11-23-20(22)24-19(15)21/h3-8,10-11H,9,12H2,1-2H3,(H4,21,22,23,24)
InChi Key
MYQAUKPBNJWPIE-UHFFFAOYSA-N
Handling
Protect from air and moisture

Product Categories/Family for GW2580 biochemical

Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase Inhibitors and Biochemicals; Enzyme Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Kinase Inhibitors and EZSolution Ready-to-Use Products and Biochemicals; Biochemicals (A-Z)

Structure of GW2580 biochemical

EZSolution GW2580 Biochemical – Cat# MBS843003

Other Notes

Small volumes of GW2580 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GW2580 purchase

MBS843003 is a biochemical targeting GW2580. Also known as EZSolution GW2580.
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