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I-CBP112

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843030

Background: I-CBP112 is a selective CBP/EP300 bromodomain inhibitor (IC?? values of 170 nM, 170 nM, 151 nM and 625 nM for CREBBP(Alphascreen), CREBBP(BLI), CREBBP(ITC) and EP300(ITC),respectively). Selective for CBP and p300 over ATAD2, BAZ2B, BRD2(2),… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
I-CBP112, Biochemical
Full Product Name
I-CBP112
Product Gene Name
I-CBP112 biochemical
Product Synonym Names
1-[7-(3,4-Dimethoxyphenyl)-9-[[(3S)-1-methylpiperidin-3-yl]methoxy]-2,3,4,5-tetrahydro-1,4-benzoxazepin-4-yl]propan-1-one
Form/Format
Appearance: White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
468.59
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
Yes
PubChem CID
90488984
Solubility/Reconstitution Instructions
DMSO (>40 mg/ml)
SMILES
CCC(=O)N1CCOC2=C(C1)C=C(C=C2OCC3CCCN(C3)C)C4=CC(=C(C=C4)OC)OC
InChi
InChI=1S/C27H36N2O5/c1-5-26(30)29-11-12-33-27-22(17-29)13-21(20-8-9-23(31-3)24(14-20)32-4)15-25(27)34-18-19-7-6-10-28(2)16-19/h8-9,13-15,19H,5-7,10-12,16-18H2,1-4H3/t19-/m0/s1
InChi Key
YKNAKDFZAWQEEO-IBGZPJMESA-N
Handling
Protect from air and light

Product Categories/Family for I-CBP112 biochemical

Enzyme Inhibitors; Bromodomain InhibitorsEnzyme Inhibitors; Enzyme Inhibitors (A-Z) Biochemicals; Enzyme Inhibitors; Bromodomain InhibitorsBiochemicals; Enzyme Inhibitors; Enzyme Inhibitors (A-Z) Epigenetics; Reader Domains; Bromodomains; Bromodomain Inhi

Structure of I-CBP112 biochemical

I-CBP112 Biochemical – Cat# MBS843030

Other Notes

Small volumes of I-CBP112 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for I-CBP112 purchase

MBS843030 is a biochemical targeting I-CBP112.
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