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XEN445

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843060

Background: XEN445 is a potent and selective endothelial lipase (EL) inhibitor. It displays good ADME and PK properties and shows in vivo efficacy in raising plasma HDL cholesterol concentration in mice. More details

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Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
XEN445, Biochemical
Full Product Name
XEN445
Product Gene Name
XEN445 biochemical
Product Synonym Names
(S)-2-(3-(pyridin-2-ylmethoxy)pyrrolidin-1-yl)-5-(trifluoromethyl)benzoic acid
Form/Format
Appearance: White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Molecular Weight
366.33
CAS Number
1515856-92-4
Structure Available?
Y
Salt Form
No
Cell-Permeable?
Yes
Solubility/Reconstitution Instructions
DMSO
SMILES
O=C(O)C1=CC(C(F)(F)F)=CC=C1N2C[C@@H](OCC3=NC=CC=C3)CC2
InChi
InChI=1S/C18H17F3N2O3/c19-18(20,21)12-4-5-16(15(9-12)17(24)25)23-8-6-14(10-23)26-11-13-3-1-2-7-22-13/h1-5,7,9,14H,6,8,10-11H2,(H,24,25)/t14-/m0/s1
InChi Key
NBGRERFNOKZQLO-AWEZNQCLSA-N
Handling
Protect from air and light

Product Categories/Family for XEN445 biochemical

Enzyme Inhibitors; Lipase InhibitorsBiochemicals; Enzyme Inhibitors; Lipase InhibitorsBiochemicals; Biochemicals (A-Z)

Structure of XEN445 biochemical

XEN445 Biochemical – Cat# MBS843060

Other Notes

Small volumes of XEN445 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for XEN445 purchase

MBS843060 is a biochemical targeting XEN445.
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