AG-014699 phosphate

Name: Ag-014699 Phosphate; MyBioSource
Brand: MyBioSource
SKU: MBS843075
Price: 205 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS843075

Background: AG-014699 phosphate is a potent, cell-permeable inhibitor of PARP1 with Ki of 1.4 nM. It selectively binds to PARP 1 and inhibits the PARP1-mediated DNA repair, thus potentiating the genomic instability and apoptosis. Displays antineoplastic… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

AG-014699 phosphate, Biochemical

Full Product Name

AG-014699 phosphate

Product Synonym Names

8-Fluoro-2-(4-((methylamino)methyl)phenyl)-4,5-dihydro-1H-azepino[5,4,3-cd]indol-6(3H)-one phosphate; Rucaparib; PF-01367338

Form/Format

Appearance: Light yellow to yellow solid

Purity/Purification

>=98% by HPLC

Preparation and Storage

At -20 degree C
Shelf Life: 36 months

Molecular Weight

421.36

CAS Number

459868-92-9

Structure Available?

Yes

Salt Form

Cell-Permeable?

yes

PubChem CID

9931953

Solubility/Reconstitution Instructions

DMSO (~20 mg/ml)

SMILES

CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=CC(=CC(=C34)N2)F.OP(=O)(O)O

InChi

InChI=1S/C19H18FN3O.H3O4P/c1-21-10-11-2-4-12(5-3-11)18-14-6-7-22-19(24)15-8-13(20)9-16(23-18)17(14)15;1-5(2,3)4/h2-5,8-9,21,23H,6-7,10H2,1H3,(H,22,24);(H3,1,2,3,4)

InChi Key

FCCGJTKEKXUBFZ-UHFFFAOYSA-N

Handling

Protect from air and moisture

Product Categories/Family for AG-014699 phosphate biochemical

Enzyme Inhibitors; Poly (ADP-ribose) Polymerase (PARP) InhibitorsEnzyme Inhibitors; Enzyme Inhibitors (A-Z) Biochemicals; Enzyme Inhibitors; Poly (ADP-ribose) Polymerase (PARP) InhibitorsBiochemicals; Enzyme Inhibitors; Enzyme Inhibitors (A-Z) Epigenetics

Other Notes

Small volumes of AG-014699 phosphate biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AG-014699 phosphate purchase

MBS843075 is a biochemical targeting AG-014699 phosphate.

AG-014699 phosphate

Product Overview

Product Categories/Family for AG-014699 phosphate biochemical

Structure of AG-014699 phosphate biochemical

Related Product Information for AG-014699 phosphate biochemical

Other Notes

Searchable Terms for AG-014699 phosphate purchase